This webinar focuses on the specific application of Raw Material Analysis.
Join us on August 15, 2016 at 10.00 – 11.00 PM for this free 60-minute webinar.
In this webinar you will learn:
• A raw material analysis application solution showcasing the use of NIR in testing system design and compliance review
• Best practices to identify adulterants in raw materials and identify finished products for compliance using an ASD instrument
• An example of the successful development of a unique library featuring more than 4000 validated reference standards for rapid non- destructive identification analysis using ASD software and spectrometers
About our speaker:
Danielle Baumgart is the President of Priority One Nutritional Supplements Inc. since 1994; Priority One is an international supplement company line with more than 120 products sold directly to physicians. Danielle also serves as the Vice President of Quality Control for First Priority Manufacturing Inc since 2000. First Priority Manufacturing Inc. specializes in custom manufacturing in the United States, Mexico, United Kingdom, The UAE, Singapore, Malaysia, and the Caribbean.
Differential Scanning Calorimetry (DSC) has a long history of playing a vital role in biopharmaceutical development. From candidate selection to formulation development, stability monitoring and bio-similarity assessment, DSC remains one of the top assays utilized in the pharmaceutical industry during the development and approval of protein-based therapeutics.
There is familiarity in the biopharmaceutical industry with the basic concept of DSC as it relates to protein stability. As a protein is heated in a DSC experiment, the midpoint of thermal denaturation transition(s) (termed Tm) is/are measured, and ranking of stability based on higher Tm values is performed (whether different constructs or different formulations of a protein, etc.). Although extremely useful for protein stability assessment, Tm values alone may not always reveal some characteristics of a protein molecule that can be highly dependent on the solution environment.
DSC analyses can be used to probe even deeper when other parameters obtained from the assay are also used (onset temperature of unfolding, peak width and peak area), even when it appears that a Tm does not shift. In this presentation, real-life examples of taking DSC analysis “deeper” will be presented. These examples will include monitoring the binding of a metal ion to an enzyme, high(er) throughput formulation development using a DOE approach for a monoclonal antibody, and using DSC to assist in the development of a complex purification process for a fusion protein.
More informationMeasurement type: Microcalorimetry
Date: Tuesday, August 16, 2016 - Tuesday, August 16, 2016
Time: 18.30 - 19.30
Learn how to improve process control, detect leaks or upsets, and meet compliance requirements with online organics monitoring using the InnovOx TOC Analyzer and Supercritical Water Oxidation (SCWO) technology.
Topics to be covered include:
Overview of organics monitoring for utility, process, and waste waters
Practical use of organic carbon data for process optimization, leak detection, and compliance
Benefits of the InnovOx TOC Analyzer and SCWO technology in challenging applications, such as measurement of brine samples
Duration: 30-minute presentation, 15-minute Q&A session
Location/Language: Online / English
Presenter: Dondra Biller, PhD Lead Product Application Specialist
The class of flow analysis techniques based on monitoring a chemical reaction (reduction, oxidation, or decomposition) as the temperature is increased is a very versatile and powerful toolbox for the characterization of catalysts and other chemically active surfaces. These techniques, known as Temperature Programed methods (TPx) includes Temperature Programmed Reduction (TPR), Temperature Programmed Oxidation (TPO), Temperature Programmed Decomposition (TPD). TPx methods can quantitate the number of active sites as well as provide insight into the relative strengths of the sites. This webinar will review some of these methods, the information that can be gained from them, and some hints on their implementation.